Yes! You can quickly switch between the first 9 profiles in any app using keyboard shortcuts. Just press Cmd+1, Cmd+2, ..., up to Cmd+9 (or Ctrl+1 to Ctrl+9 on Windows/Linux).
To see which shortcut corresponds to each profile, open the Profiles menu from the app menu or hover over the profiles in the profile bar. The shortcut will be shown next to the name of the profile.

